NOVEL SULPHAMOYLATED 2-METHOXY ESTRADIOL DERIVATIVES INHIBIT BREAST CANCER MIGRATION BY DISRUPTING MICROTUBULE TURNOVER AND ORGANIZATION

Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization

Abstract Background The estrogen metabolite 2-methoxyestradiol (2ME2) and a number of synthesised derivatives have been shown to bind to microtubules thereby arresting cancer cells in mitosis which leads to apoptosis.In interphase cells, microtubules play an important role in the delivery of proteins to subcellular locations including the focal adh

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The Third Currency War as an Effect of Post-Crisis Changes in the International Currency System. The Risk Aspect - the Case Analyses of Brazil

Aim/purpose - The objectives of the Potassium paper include: identification of factors that influence the directions of fluctuations of foreign exchange rates seen as manifestations of currency wars; description of the most important forms of currency wars conducted in the contemporary global economy (including in particular the currently observed

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The Multi-Switching Sliding Mode Combination Synchronization of Fractional Order Non-Identical Chaotic System with Stochastic Disturbances and Unknown Parameters

This paper deals with the issue of the multi-switching sliding mode combination synchronization (MSSMCS) of fractional order (FO) chaotic systems with different structures and unknown parameters under double stochastic disturbances (SD) utilizing the multi-switching synchronization method.The stochastic disturbances are considered as nonlinear unce

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OPTIMAL ALLOCATION OF TCSC DEVICES FOR THE ENHANCEMENT OF ATC IN DEREGULATED POWER SYSTEM USING FLOWER POLLINATION ALGORITHM

This paper proposes a best possible distribution of Thyristor Controlled Series Compensator (TCSC) to progress the Available Transfer Capability (ATC) of power transactions between Gardening Apron sources and sink areas in the deregulated power system.The principle of TCSC device is to balance the inductive voltage drop in the line by an introduced

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